IRS Notice: Business owners may be able to benefit from the home office deduction. Taxpayers who use their home for business may be eligible to claim a home office deduction. It allows qualifying taxpayers to deduct certain home expenses on their tax return. This can reduce the amount of the taxpayer’s taxable income. Here are some things to help taxpayers understand the home office deduction and whether they can claim it: The home office deduction is available to both homeowners and renters.